2019/07/26_OTUs/phylosymbiotic _名词解释

可执行的分类操作单位，主要是按照16sDNA测序结果计算遗传距离，人为规定遗传距离，然后依此距离区别微生物类群的分类单位，为了形象直观，并有说服力，往往会和已知菌一起做聚类，从而完成微生物的种属归属鉴定。

An operational taxonomic unit (OTU) is an operational definition used to classify groups of closely related individuals.

 For several years, OTUs have been the most commonly used units of microbial diversity, especially when analyzing small subunit 16S or 18S rRNA marker gene sequence datasets. 

phylosymbiotic: In the field of microbiome research, a group of species is said to show a phylosymbiotic signal if the degree of similarity between the species' microbiomes recapitulates to a significant extent their evolutionary history. 物种微生物群之间的相似程度在很大程度上重新概括了它们的进化史。In other words, a phylosymbiotic signal among a group of species is evident if their microbiome similarity dendrogram could significantly recapitulate their host's phylogenic tree. For the analysis of the phylosymbiotic signal to be reliable, environmental differences that could shape the host-microbiome should be either eliminated or accounted for. One plausible mechanistic explanation for such phenomena could be, for example, a result of host immune genes that rapidly evolve in a continues arms race with members of its microbiome.

 

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