R中报错Error in mut[, pos] - 1 : non-numeric argument to binary operator

数据不是数值型，转换成数值型即可解决问题

as.numeric()

> sigs.input=mut.to.sigs.input(mut.ref =sample.mut.ref ,sample.id ="Tumor_Sample_Barcode" ,chr ="Chromosome" ,pos ="End_Position" ,ref="Reference_Allele",alt ="Tumor_Seq_Allele2" ,bsg = BSgenome.Hsapiens.UCSC.hg38)
Error in mut[, pos] - 1 : non-numeric argument to binary operator
> head(maf$End_Position)
[1] "965125"  "973929"  "1014228" "1041194" "1204185" "1285574"
> class(maf$Start_Position)
[1] "character"
> sample.mut.ref$End_Position=as.numeric(sample.mut.ref$End_Position)
> sigs.input=mut.to.sigs.input(mut.ref =sample.mut.ref ,sample.id ="Tumor_Sample_Barcode" ,chr ="Chromosome" ,pos ="End_Position" ,ref="Reference_Allele",alt ="Tumor_Seq_Allele2" ,bsg = BSgenome.Hsapiens.UCSC.hg38)
>

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